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Translation and validation of the arabic version of the revised 15-item myasthenia gravis quality-of-life questionnaire



Article type: Published article

Abstract

INTRODUCTION: We sought to translate, culturally adapt, and assess the Arabic version of the 15-item myasthenia gravis quality-of-life revised scale (MGQOL15R). METHODS: We assessed reliability with Cronbach alpha; reproducibility with intraclass correlation coefficient (ICC); validity with Spearman correlations for myasthenia gravis (MG)-specific activities of daily living (MG-ADL), MG composite (MGC) score, and MG manual muscle test (MG-MMT) and with MGQOL15R in patients with different disease severity through the Kruskal-Wallis test; and sensitivity to change with Wilcoxon signed-rank test. RESULTS: In 65 enrolled patients, the mean MGQOL15R score was 10.84 +/- 8.11 (alpha = 0.94, ICC = 0.95). The correlation coefficients between MGQOL15R and MGC, MG-ADL, and MG-MMT scores were 0.75, 0.75, and 0.74, respectively (P < 0.001). MGQOL15R scores were significantly higher (worse) in patients with more severe disease at baseline and significantly lower (better) in improved patients at follow-up. DISCUSSION: The Arabic version of MGQOL15R is valid, reliable, stable, and sensitive to changes. Muscle Nerve, 2017.


Full citation

Alanazy, M. H., et al. (2017). "Translation and validation of the arabic version of the revised 15-item myasthenia gravis quality-of-life questionnaire." Muscle Nerve.


Methodology

Methods Condition Gender Age Country Setting Sample size
Patients Both Saudi Arabia
Healthcare Facility 65

Number of items

15 items

Training

Measure does not require training

Required time

Less than 5 min

Access measure

dranazy@gmail.com






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Articles last updated: December 2020